- All categories
- Cosmetics
- Medical devices
- Biocidal products
- Detergents
- Food supplements
- Medical surgical devices
- Hazardous mixtures
- E-Cigs, E-liquids
MTT - Cytotoxicity Evaluation through an In Vitro Assay
The MTT test allows the evaluation of the potential release of cytotoxic substances from a cosmetic product (in vitro cultures of fibroblasts, keratinocytes, oral, nasal, tracheal, bronchial, pulmonary, intestinal, vaginal mucosal cells, corneal cells.../reconstructed epidermis, reconstructed oral epithelium, reconstructed vaginal epithelium, reconstructed ocular epithelium...).
In Vitro Evaluation of the Cytotoxicity of Medical Devices
The test is performed on fibroblast cell cultures to assess the potential release of cytotoxic substances from a Class I / IIa / IIb / III medical device. The analysis is carried out in accordance with the ISO standard for the biological evaluation of medical devices (UNI EN ISO 10993-5).
NRU - Evaluation of Potential Skin/Ocular Irritation
The NRU test allows the evaluation of a product's toxicity on keratinocyte cultures and provides a good approximation of the product's gentleness and tolerance (potential irritant power) when applied to the skin and/or mucous membranes.
In Vitro Phototoxicity Assay 3T3 NRU
The 3T3 NRU in vitro phototoxicity assay allows to verify whether the tested product is phototoxic, meaning it exhibits toxic effects after light exposure on BALB/C 3T3 murine fibroblast cell cultures.
In Vitro Skin Corrosivity Evaluation
The purpose of the test is to evaluate the in vitro skin corrosivity of a product.
In Vitro Skin Irritation Test on Reconstructed Epidermis
The test involves applying the product to be tested (as is) on a reconstructed human epidermis model, followed by the evaluation of cell viability (MTT). The reduction in tissue viability exposed to chemical agents compared to negative controls is an indicator of potential skin irritation.
In Vitro Skin Irritation Test
The test is performed on reconstructed epidermis and allows the evaluation of the potential irritancy of substances, without the use of animal testing.
Short Time Exposition
The Short Time Exposition (STE) method is a test based on the evaluation of in vitro cytotoxicity, performed on a confluent monolayer of rabbit corneal cells (SIRC).
Ocular Irritation Test on Reconstructed Epithelium
The purpose of the test is to apply the tested sample to the surface of the reconstructed ocular epithelium and quantitatively determine cell viability, which allows for the classification of the sample as irritant or non-irritant.
In Vitro Evaluation of the Potential Pro-Sensitizing Effect of Medical Devices
The purpose of the test is to evaluate the absence of pro-sensitizing effects of the tested sample.
In Vitro Evaluation of the Potential Pro-Sensitizing Effect
he purpose of the test is to evaluate the absence of pro-sensitizing effects of the tested sample.
SCREENING TEST - Preliminary Evaluation of the Potential Pro-Sensitizing Action
This test is used as a screening method and provides a preliminary evaluation of the potential pro-sensitizing action of a product through the assessment of cellular morphology (Light scattering). Any confirmation of the product's pro-sensitizing potential can be made by evaluating the modulation of the expression of two co-stimulatory molecules, CD86 and CD54.